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Female to Male Changes

Females transitioning to males (FTM) may experience the following permanent effects of testosterone:

  • Atrophy of the uterus and ovaries, resulting in sterility
  • Baldness; hair loss, especially at temples and crown of head
  • Beard and mustache growth
  • Deepening of the voice
  • Enlargement of the clitoris
  • Increased growth of body hair
  • Sterility

Temporary changes, which are reversible after HT is stopped, include the following:

  • Behavioral developments associated with testosterone production during male puberty:
    • Aggression
    • Increased libido
  • Development of acne, similar to male puberty
  • Increased muscle mass and strength
  • Increase in number of red blood cells
  • Redistribution of fat from breasts, hips, and thighs to abdominal area

Risks associated with FTM testosterone therapy include the following:

  • Breast cancer
  • Cancer of endometrium
  • Diabetes
  • High cholesterol
  • Hypertension
  • Liver disease

Tobacco increases a person's risk for disease and complications. A general medical checkup is necessary before treatment, as well as a review of patient and family health history.


  • « Male to Female MTF Changes
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  • Physician-developed and -monitored.
    Original Date of Publication: 01 Aug 2001
    Reviewed by: Stanley J. Swierzewski, III, M.D.
    Last Reviewed: 04 Dec 2007

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    This page last modified: 16 Mar 2009

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